{"id":22638,"date":"2024-03-25T10:29:55","date_gmt":"2024-03-25T09:29:55","guid":{"rendered":"https:\/\/www.liebscher-bracht.com\/en\/?page_id=22638"},"modified":"2024-05-24T10:30:50","modified_gmt":"2024-05-24T08:30:50","slug":"healing-knee-osteoarthritis","status":"publish","type":"page","link":"https:\/\/www.liebscher-bracht.com\/en\/facts-and-figures\/healing-knee-osteoarthritis\/","title":{"rendered":"A Study That&#8217;s Changing the Game for Knee Osteoarthritis"},"content":{"rendered":"\n\t<section class=\"section\" id=\"section_862978385\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n<div class=\"row show-for-small\"  id=\"row-737261403\">\n\n\t<div id=\"col-715326966\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h1 class=\"p1\">A Study That&#8217;s Changing the Game for Knee Osteoarthritis<\/h1>\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-715326966 > .col-inner {\n  margin: 20px 0px -30px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n<\/div>\n\n  <div class=\"banner has-hover\" id=\"banner-1903163897\">\n          <div class=\"banner-inner fill\">\n        <div class=\"banner-bg fill\" >\n            <img decoding=\"async\" width=\"1020\" height=\"364\" src=\"https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/heilprozesse-bei-knie-arthrose-1180-420-28032023-liebscher-bracht-1024x365-1.webp\" class=\"bg attachment-large size-large\" alt=\"MRI of knees\" \/>                        <div class=\"overlay\"><\/div>            \n\t<div class=\"is-border\"\n\t\tstyle=\"border-width:0px 0px 0px 0px;margin:0px 0px -21px px;\">\n\t<\/div>\n                    <\/div>\n\t\t\n        <div class=\"banner-layers container\">\n            <div class=\"fill banner-link\"><\/div>            \n   <div id=\"text-box-2006740705\" class=\"text-box banner-layer hide-for-small x100 md-x100 lg-x100 y20 md-y20 lg-y20 res-text\">\n                                <div class=\"text-box-content text dark\">\n              \n              <div class=\"text-inner text-right\">\n                  \n<p class=\"p1\">\u00a0<\/p>\n<h1 class=\"p1\">A Study That&#8217;s Changing the Game for Knee Osteoarthritis<\/h1>\n              <\/div>\n           <\/div>\n                            \n<style>\n#text-box-2006740705 {\n  margin: 0px 20px 0px 0px;\n  width: 60%;\n}\n#text-box-2006740705 .text-box-content {\n  font-size: 100%;\n}\n<\/style>\n    <\/div>\n \n   <div id=\"text-box-4702511\" class=\"text-box banner-layer x100 md-x100 lg-x100 y100 md-y100 lg-y100 res-text\">\n                                <div class=\"text-box-content text dark\">\n              \n              <div class=\"text-inner text-right\">\n                  \n\t<div id=\"text-2961275583\" class=\"text box\">\n\t\t\n<p style=\"text-align: right;\">\u00a9 Suttha Burawonk | shutterstock.com<\/p>\n\t\t\n<style>\n#text-2961275583 {\n  text-align: right;\n}\n<\/style>\n\t<\/div>\n\t\n              <\/div>\n           <\/div>\n                            \n<style>\n#text-box-4702511 {\n  margin: 0px 20px 0px 0px;\n  width: 60%;\n}\n#text-box-4702511 .text-box-content {\n  font-size: 100%;\n}\n<\/style>\n    <\/div>\n \n        <\/div>\n      <\/div>\n\n            \n<style>\n#banner-1903163897 {\n  padding-top: 150px;\n}\n#banner-1903163897 .overlay {\n  background-color: rgba(0, 0, 0, 0.372);\n}\n#banner-1903163897 .banner-bg img {\n  object-position: 21% 46%;\n}\n@media (min-width:550px) {\n  #banner-1903163897 {\n    padding-top: 420px;\n  }\n}\n<\/style>\n  <\/div>\n\n\n\t\t<\/div>\n\n\t\t\n<style>\n#section_862978385 {\n  padding-top: 0px;\n  padding-bottom: 0px;\n}\n<\/style>\n\t<\/section>\n\t\n\n\t<section class=\"section\" id=\"section_1991191872\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n<div class=\"row\"  id=\"row-695632640\">\n\n\t<div id=\"col-702867526\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\t<div id=\"gap-540782085\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-540782085 {\n  padding-top: 30px;\n}\n<\/style>\n\t<\/div>\n\t\n<div class=\"breadcrumbs\" typeof=\"BreadcrumbList\" vocab=\"http:\/\/schema.org\/\"><span property=\"itemListElement\" typeof=\"ListItem\"><a property=\"item\" typeof=\"WebPage\" title=\"Gehe zu Liebscher &amp; Bracht - The Pain Specialists.\" href=\"https:\/\/www.liebscher-bracht.com\/en\/\" class=\"home\"><span property=\"name\">Start<\/span><\/a><meta property=\"position\" content=\"1\"><\/span> &gt; <span property=\"itemListElement\" typeof=\"ListItem\"><a property=\"item\" typeof=\"WebPage\" title=\"Gehe zu Protected: blog test.\" href=\"https:\/\/www.liebscher-bracht.com\/en\/blog-test\/\" class=\"post-root post post-post\"><span property=\"name\">Protected: blog test<\/span><\/a><meta property=\"position\" content=\"2\"><\/span><\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n<div class=\"row align-center\"  id=\"row-739369320\">\n\n\t<div id=\"col-664164885\" class=\"col medium-12 small-12 large-8\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<p><i><span style=\"font-weight: 400;\">There&#8217;s no cure for knee arthritis.\u00a0<\/span><\/i><\/p>\n<p><i><span style=\"font-weight: 400;\">You&#8217;ll have to accept that this is the way it is from now on.\u00a0<\/span><\/i><\/p>\n<p><i><span style=\"font-weight: 400;\">Focus on managing your symptoms.<\/span><\/i><\/p>\n<p><span style=\"font-weight: 400;\">These are phrases arthritis patients commonly hear while sitting on the examination table. For decades, doctors have thought that people suffering from osteoarthritis had no choice but to live with the pain. Osteoarthritis is considered to be an incurable condition, with treatment options limited to delaying the progression of the disease for as long as possible. <sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-1\">1)<\/a><\/sup><sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-2\">2)<\/a><\/sup><sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-3\">3)<\/a><\/sup><\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, the results of a 2013 study by Professor Floris Lafeber at the University Medical Centre Utrecht, Netherlands, are changing how medical professionals think about osteoarthritis.\u00a0<\/span><\/p>\n<h3>Knee Joint Distraction (KJD)<\/h3>\n<p><span style=\"font-weight: 400;\">Professor Lafeber and his team researched a treatment for knee osteoarthritis called knee joint distraction (KJD).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Distraction is an invasive surgical procedure that temporarily separates the ends of two bones that form a joint. Space is created between the ends of the bones by fixing a frame outside of the affected area. Each bone is drilled in several places, and metal pins are inserted into the holes. The pins protrude from the skin to attach to a metal frame. Joint distraction resets the bones so that they can grow back correctly.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Joint distraction is not new. For over 100 years, bone distraction has been used to lengthen bones. <\/span><i><span style=\"font-weight: 400;\"><sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-4\">4)<\/a><\/sup> <\/span><\/i><span style=\"font-weight: 400;\">The surgery has proven very effective, especially when healing complicated bone fractures.<\/span><\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-750056961\" class=\"col medium-12 small-12 large-4\"  >\n\t\t\t\t<div class=\"col-inner\" style=\"background-color:rgb(245, 241, 233);\" >\n\t\t\t\n\t\t\t\n<div class=\"row align-center\"  id=\"row-287410928\">\n\n\t<div id=\"col-1752418934\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\t<div id=\"text-575784464\" class=\"text\">\n\t\t\n<h3>Read Study<\/h3>\n<p style=\"line-height: 24px;\"><span style=\"font-size: 80%;\">Wiegant, K., van Roermund, P. M., Intema, F., Cotofana, S., Eckstein, F., Mastbergen, S. C., & Lafeber, F. P. (2013). Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis.\u00a0<em>Osteoarthritis and cartilage<\/em>,\u00a021(11), 1660\u20131667.<\/span>\u00a0<a  href=\"https:\/\/doi.org\/10.1016\/j.joca.2013.08.006\"  target=\"_blank\" rel=\"nofollow noopener\" data-line-height=\"xs\" dpc-external=\"true\"  target=\"_blank\" ><img decoding=\"async\" class=\"alignnone wp-image-188349\" style=\"margin-bottom: 5px;\" src=\"https:\/\/www.liebscher-bracht.com\/wp-content\/uploads\/2022\/01\/Share-External-Link.svg\" alt=\"Externer Link Icon\" width=\"16\" height=\"15\" \/><\/a><\/p>\n\t\t\n<style>\n#text-575784464 {\n  text-align: left;\n}\n<\/style>\n\t<\/div>\n\t\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1752418934 > .col-inner {\n  padding: 30px 30px 0px 30px;\n  margin: 0px 0px -20px 0px;\n}\n@media (min-width:550px) {\n  #col-1752418934 > .col-inner {\n    padding: 20px 30px 10px 30px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\n<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1338709325\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>Why Knee Joint Distraction?<\/h3>\n<p><span style=\"font-weight: 400;\">Professor Lafeber and his team wanted to determine if increasing the distance between the knee bones could reduce pain and improve mobility.<sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-5\">5)<\/a><\/sup> What ended up happening was that the team made a discovery that could prove to be groundbreaking for the treatment of osteoarthritis.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Previously, the team had conducted clinical studies on bone distraction for ankle osteoarthritis.<sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-6\">6)<\/a><\/sup><sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-7\">7)<\/a><\/sup> The positive results of these studies<sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-8\">8)<\/a><\/sup><sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-9\">9)<\/a><\/sup> led the team to hypothesise that bone distraction may benefit knee osteoarthritis.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">\u00a0<\/span>The Study<\/h3>\n<p><span style=\"font-weight: 400;\">For the 2013 study, 20 participants were selected. All were physically active people between the ages of 32 and 57 suffering from stage 4 (a.k.a end stage) knee osteoarthritis. (Stage 4 is the most severe stage of osteoarthritis.) All participants were experiencing loss of function (limited mobility) and persistent pain. Conservative knee osteoarthritis treatments had been exhausted \u2014 the next step would have been knee replacement surgery. (Considering the age of the participants and the 15 to 20-year lifespan of a knee replacement, a second replacement would probably be necessary.)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Each participant&#8217;s distraction was applied to their upper and lower leg bones, increasing the space in the participants&#8217; knees. The goal of the procedure was to create space in the knee that would remain even after the distraction had been removed, delaying the need for knee replacement surgery.<\/span><\/p>\n<h3>Potential Complications During Distraction<\/h3>\n<p><span style=\"font-weight: 400;\">There are potential complications that can occur during distraction.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Exposing the distraction device to external forces, like falling and landing on the device or catching it on an item of clothing, could impact the bones.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Patients may develop &#8216;pin-track infection&#8217;.<sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-10\">10)<\/a><\/sup> This is an infection in the areas where the pins protrude. A common side effect of pin-track infection is inflammation in the area.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In a worst-case scenario, germs could penetrate the bones.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Since the distraction device has to be worn for many weeks, a complication will likely occur.<\/span><\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1429215171\" class=\"col medium-8 small-12 large-8\"  >\n\t\t\t\t<div class=\"col-inner text-left\"  >\n\t\t\t\n\t\t\t\n\t<div id=\"text-704169982\" class=\"text\">\n\t\t\n<h3>\u00a0<\/h3>\n<h3>Results of the Study<\/h3>\n<p><span style=\"font-weight: 400;\">The procedure was successful for all participants.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Most developed a pin-track infection, which was treated with antibiotics.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Immediately after removing the distraction device, the participants found that their knee mobility was restricted. Reduced movement was expected since immobilised joints stiffen. Within a few weeks, the stiffness was gone entirely.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">After only three months, participants&#8217; pain had subsided considerably, with a significant increase in knee mobility. Participants&#8217; knees continued to heal steadily in the six months that followed. A one-year follow-up showed that the range of motion of participants&#8217; knees had continued to increase, and their pain had decreased.<sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-11\">11)<\/a><\/sup><\/span><\/p>\n\t\t\n<style>\n#text-704169982 {\n  text-align: left;\n}\n<\/style>\n\t<\/div>\n\t\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1429215171 > .col-inner {\n  padding: 0px 0px 0px 0px;\n  margin: 0px 0px -45px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n\n\t<div id=\"col-1547182929\" class=\"col medium-4 small-12 large-4\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\t<div class=\"img has-hover x md-x lg-x y md-y lg-y\" id=\"image_136940470\">\n\t\t\t\t\t\t\t\t<div class=\"img-inner image-cover dark\" style=\"padding-top:100%;margin:70px 0px 0px 0px;\">\n\t\t\t<img decoding=\"async\" width=\"800\" height=\"800\" src=\"https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/knochen-distraktion-knie-arthrose-grafik-13062023-liebscher-bracht..webp\" class=\"attachment-large size-large\" alt=\"Graphic of a knee distraction\" srcset=\"https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/knochen-distraktion-knie-arthrose-grafik-13062023-liebscher-bracht..webp 800w, https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/knochen-distraktion-knie-arthrose-grafik-13062023-liebscher-bracht.-300x300.webp 300w, https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/knochen-distraktion-knie-arthrose-grafik-13062023-liebscher-bracht.-150x150.webp 150w, https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/knochen-distraktion-knie-arthrose-grafik-13062023-liebscher-bracht.-768x768.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n<style>\n#image_136940470 {\n  width: 100%;\n}\n<\/style>\n\t<\/div>\n\t\n<p data-padding=\"40px\"><span style=\"font-size: 80%;\">Graphic of an external knee distraction (\u00a9 Liebscher & Bracht<\/span><\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n<div class=\"row\"  id=\"row-2063353180\">\n\n\t<div id=\"col-1740662419\" class=\"col medium-8 small-12 large-8\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>\u00a0<\/h3>\n<h3>The Unexpected Discovery That&#8217;s Breaking Ground<\/h3>\n<p><span style=\"font-weight: 400;\">After the distraction device was removed, the research team documented the participants&#8217; progress with magnetic resonance imaging (MRI) and X-rays.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The team made an unexpected discovery: cartilage had regenerated.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The deteriorated cartilage was thicker, and areas of exposed bone were covered with cartilage.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The MRIs showed that the newly formed cartilage had the same properties as healthy cartilage<sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-12\">12)<\/a><\/sup>; it could withstand the stress and force of bearing weight.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The regenerated cartilage was not a temporary phenomenon. A long-term observation showed that the cartilage was still thicker seven years after the distraction.<sup><a href=\"#\" class=\"lnb-footnote-anchor\" data-group=\"lnb-footnote-13\">13)<\/a><\/sup><\/span><\/p>\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1740662419 > .col-inner {\n  padding: 5px 0px 0 0px;\n  margin: 0px 0px -30px 0px;\n}\n@media (min-width:550px) {\n  #col-1740662419 > .col-inner {\n    padding: 0px 0px 0 0px;\n    margin: 0px 0px 0 0px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\n\n\t<div id=\"col-606065133\" class=\"col medium-4 small-12 large-4\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\t<div class=\"img has-hover x md-x lg-x y md-y lg-y\" id=\"image_284532276\">\n\t\t\t\t\t\t\t\t<div class=\"img-inner dark\" style=\"margin:42px 0px -20px 0px;\">\n\t\t\t<img decoding=\"async\" width=\"1020\" height=\"1020\" src=\"https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/heilprozesse-bei-knie-arthrose-grafik-kniegelenk-06.04.2023-liebscher-bracht-1024x1024-1-1024x1024.webp\" class=\"attachment-large size-large\" alt=\"Graphic of a leg bone and muscles\" srcset=\"https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/heilprozesse-bei-knie-arthrose-grafik-kniegelenk-06.04.2023-liebscher-bracht-1024x1024-1.webp 1024w, https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/heilprozesse-bei-knie-arthrose-grafik-kniegelenk-06.04.2023-liebscher-bracht-1024x1024-1-300x300.webp 300w, https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/heilprozesse-bei-knie-arthrose-grafik-kniegelenk-06.04.2023-liebscher-bracht-1024x1024-1-150x150.webp 150w, https:\/\/www.liebscher-bracht.com\/en\/wp-content\/uploads\/2024\/03\/heilprozesse-bei-knie-arthrose-grafik-kniegelenk-06.04.2023-liebscher-bracht-1024x1024-1-768x768.webp 768w\" sizes=\"(max-width: 1020px) 100vw, 1020px\" \/>\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n<style>\n#image_284532276 {\n  width: 100%;\n}\n<\/style>\n\t<\/div>\n\t\n<p style=\"text-align: left;\"><span style=\"font-size: 80%;\">Healthy knee joint with normal bone distance\u00a0(\u00a9 peakanucha | shutterstock.com)<\/span><\/p>\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-606065133 > .col-inner {\n  padding: 0 0px 0px 0px;\n  margin: 70px 0px -50px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n\n\t<div id=\"col-678667634\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>Knee Distraction: A Successful Treatment for End-Stage Osteoarthritis<\/h3>\n<p><span style=\"font-weight: 400;\">Professor Lafeber&#8217;s 2013 study and several follow-up studies prove that knee distraction is a viable treatment for knee osteoarthritis and can delay the need for knee replacement surgery by at least two years.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Despite the procedure and associated complications, participants were satisfied with the results of the distraction.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Considering the results of Professor Lafeber&#8217;s study and the participants&#8217; feedback, knee distraction could emerge as a treatment option for knee osteoarthritis.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Knee distraction is a desirable option for younger people with knee osteoarthritis, considering the average lifespan of knee replacements. (40% of patients with partial knee replacements and 44% with total knee replacements are younger than 65.)<\/span><\/p>\n<h3>Paving the Way for the Future<\/h3>\n<p><span style=\"font-weight: 400;\">Professor Lafeber and his team emphasise that their discovery of cartilage regeneration at the most advanced stage of osteoarthritis opens up new research opportunities and treatments, which could lead to a cure.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Since this study was conducted, The University Medical Centre in Utrecht, Netherlands, has regularly used knee distraction to treat osteoarthritis successfully. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">You don&#8217;t have to live with the pain.<\/span><\/p>\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-678667634 > .col-inner {\n  padding: 0px 0px 0 0px;\n  margin: 0px 0px -30px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n<\/div>\n<div class=\"row align-center\"  id=\"row-1080327492\">\n\n\t<div id=\"col-1705465713\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<div class=\"is-divider divider clearfix\" style=\"max-width:100%;height:1px;\"><\/div>\n<div class=\"row align-center\"  id=\"row-1659802333\">\n\n\t<div id=\"col-768850381\" class=\"col medium-4 small-12 large-4\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<a href=\"https:\/\/www.liebscher-bracht.com\/en\/facts-and-figures\/\" target=\"_blank\" class=\"button secondary is-smaller expand\" rel=\"noopener\"  >\n\t\t<span>Back to Research &amp; Studies<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-768850381 > .col-inner {\n  margin: 0px 0px -30px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n<\/div>\n<div class=\"is-divider divider clearfix\" style=\"max-width:100%;height:1px;\"><\/div>\n<div id=\"footnotes\" class=\"hac-scroll-to\"><div id=\"lnb-footnotes-container\"><h3 class=\"lnb-footnotes-title-h3\"><span class=\"lnb-foonotes-title\">Sources & Studies<\/span><\/h3><div class=\"lnb-footnotes-content text-readmore--collapsible collapsed\"><ul><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-1\">&uarr;1<\/a> Hunter, D. J., & Lo, G. H. (2009). The management of osteoarthritis: an overview and call to appropriate conservative treatment. The Medical clinics of North America, 93(1), 127\u2013xi<\/li><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-2\">&uarr;2<\/a> Zweers, M. C., de Boer, T. N., van Roon, J., Bijlsma, J. W., Lafeber, F. P., & Mastbergen, S. C. (2011). Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritis. Arthritis research & therapy, 13(5), 239.<\/li><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-3\">&uarr;3<\/a> Conaghan, P. G., Dickson, J., Grant, R. L., & Guideline Development Group (2008). Care and management of osteoarthritis in adults: summary of NICE guidance. BMJ (Clinical research ed.), 336(7642), 502\u2013503.<\/li><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-4\">&uarr;4<\/a> Troulis MJ, Padwa B, Kaban LB. Distraction osteogenesis: past, present, and future. Facial Plast Surg. 1998;14(3):205-15. doi: 10.1055\/s-2008-1064346. PMID: 11816193.<\/li><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-5\">&uarr;5<\/a> Wiegant, K., van Roermund, P. M., Intema, F., Cotofana, S., Eckstein, F., Mastbergen, S. C., & Lafeber, F. P. (2013). Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis. Osteoarthritis and cartilage, 21(11), 1660\u20131667.<\/li><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-6\">&uarr;6<\/a>,<a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-8\">&uarr;8<\/a> Marijnissen, A. C., van Roermund, P. M., van Melkebeek, J., & Lafeber, F. P. (2003). Clinical benefit of joint distraction in the treatment of ankle osteoarthritis. Foot and ankle clinics, 8(2), 335\u2013346.<\/li><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-7\">&uarr;7<\/a>,<a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-9\">&uarr;9<\/a> Ploegmakers, J. J., van Roermund, P. M., van Melkebeek, J., Lammens, J., Bijlsma, J. W., Lafeber, F. P., & Marijnissen, A. C. (2005). Prolonged clinical benefit from joint distraction in the treatment of ankle osteoarthritis. Osteoarthritis and cartilage, 13(7), 582\u2013588.<\/li><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-10\">&uarr;10<\/a> Lethaby, A., Temple, J., & Santy-Tomlinson, J. (2013). Pin site care for preventing infections associated with external bone fixators and pins. The Cochrane database of systematic reviews, (12), CD004551.<\/li><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-11\">&uarr;11<\/a> Intema, F., Van Roermund, P. M., Marijnissen, A. C., Cotofana, S., Eckstein, F., Castelein, R. M., Bijlsma, J. W., Mastbergen, S. C., & Lafeber, F. P. (2011). Tissue structure modification in knee osteoarthritis by use of joint distraction: an open 1-year pilot study. Annals of the rheumatic diseases, 70(8), 1441\u20131446.<\/li><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-12\">&uarr;12<\/a> Eckstein, F., Ateshian, G., Burgkart, R., Burstein, D., Cicuttini, F., Dardzinski, B., Gray, M., Link, T. M., Majumdar, S., Mosher, T., Peterfy, C., Totterman, S., Waterton, J., Winalski, C. S., & Felson, D. (2006). Proposal for a nomenclature for magnetic resonance imaging based measures of articular cartilage in osteoarthritis. Osteoarthritis and cartilage, 14(10), 974\u2013983.<\/li><li><a href=\"#\" class=\"lnb-footnote-item\" data-group=\"lnb-footnote-13\">&uarr;13<\/a> Jansen, M. P., van der Weiden, G. S., Van Roermund, P. M., Custers, R. J. H., Mastbergen, S. C., & Lafeber, F. P. J. G. (2018). Initial tissue repair predicts long-term clinical success of knee joint distraction as treatment for knee osteoarthritis. Osteoarthritis and cartilage, 26(12), 1604\u20131608.<\/li><\/ul><\/div><\/div><\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n\t\t<\/div>\n\n\t\t\n<style>\n#section_1991191872 {\n  padding-top: 0px;\n  padding-bottom: 0px;\n}\n<\/style>\n\t<\/section>\n\t\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":13,"featured_media":22640,"parent":22530,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-blank.php","meta":{"footnotes":""},"class_list":["post-22638","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/www.liebscher-bracht.com\/en\/wp-json\/wp\/v2\/pages\/22638","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.liebscher-bracht.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.liebscher-bracht.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.liebscher-bracht.com\/en\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.liebscher-bracht.com\/en\/wp-json\/wp\/v2\/comments?post=22638"}],"version-history":[{"count":28,"href":"https:\/\/www.liebscher-bracht.com\/en\/wp-json\/wp\/v2\/pages\/22638\/revisions"}],"predecessor-version":[{"id":22812,"href":"https:\/\/www.liebscher-bracht.com\/en\/wp-json\/wp\/v2\/pages\/22638\/revisions\/22812"}],"up":[{"embeddable":true,"href":"https:\/\/www.liebscher-bracht.com\/en\/wp-json\/wp\/v2\/pages\/22530"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.liebscher-bracht.com\/en\/wp-json\/wp\/v2\/media\/22640"}],"wp:attachment":[{"href":"https:\/\/www.liebscher-bracht.com\/en\/wp-json\/wp\/v2\/media?parent=22638"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}